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close this bookGuidelines to Antiretroviral Drug Therapy in Kenya (WHO; 2001; 78 pages)
View the documentFOREWORD
View the documentACKNOWLEDGMENT
Open this folder and view contentsCHAPTER ONE: INITIATING ANTIRETROVIRAL THERAPY
Open this folder and view contentsCHAPTER TWO: MONITORING AND CHANGING THERAPY
Open this folder and view contentsCHAPTER THREE: PHARMACOTHERAPEUTICS OF ARVS
Open this folder and view contentsCHAPTER FOUR: GUIDELINES FOR THE USE OF ANTIRETROVIRAL DRUGS IN PAEDIATRIC HIV INFECTION
close this folderCHAPTER FIVE: MANAGEMENT OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTED PREGNANT WOMEN AND PREVENTION OF MOTHER TO CHILD TRANSMISSION (MTCT) OF HIV
View the document5.1 Overview
View the document5.2 Factors affecting mother to child transmission
View the document5.3 Outline antenatal, intrapartum postpartum and postnatal care
View the document5.4 Antiretroviral Therapy to prevent MTCT
Open this folder and view contentsCHAPTER SIX: SPECIAL CONSIDERATIONS
Open this folder and view contentsCHAPTER SEVEN: WHEN TO STOP TREATMENT (INTERRUPTIONS)
Open this folder and view contentsCHAPTER EIGHT: GUIDELINES FOR POST EXPOSURE PROPHYLAXIS
View the documentCHAPTER NINE: ACCESS TO DRUGS IN KENYA
Open this folder and view contentsAPPENDICES
View the documentBACK COVER
 

5.1 Overview

The seroprevalence rate of HIV among pregnant women in Africa exceeds 20% in many areas. In Kenya HIV prevalence in urban sentinel sites in 1998 among pregnant women was reported to range between 4 - 10% in low seroprevalence sites to 20 - 35% in high seroprevalence sites. With the observed trends, the percentage of pregnant women who are HIV infected is increasing at an alarming rate. Upto 90% of HIV infection in pregnant women is due to heterosexual contact.

In 1 999, 1 0% of reported AIDS cases in children were under 5 years of age, out of which 90% of the HIV infection was due to MTCT With our population estimated at 28.2 million, a birth rate of 1.2 million per annum, a seroprevalence rate of 20% in mothers, and an MTCT rate of 40%, the expected number of HIV infected infants per annum in Kenya will be approximately 100,000. This is a big number that the country will find difficult to cope with.

Transmission of HIV from infected mothers to their babies can occur during the antenatal period (10 -20%), labour and delivery (35 - 50%), and breastfeeding (40 - 50%). In order to reduce MTCT these areas must be targeted. There are measures which can be put in place in the management of expectant mothers so as to reduce the rate of transmission of HIV from an infected mother to the baby. These measures include voluntary counseling and testing (VCT), antiretroviral therapy and modification of obstetric practices and replacement feeding for the baby.

With reduction of MTCT, the following benefits will be derived:

Increase in child health and survival;
Decrease in the number of HIV infected orphans;
Opportunity to improve, expand health services and strengthen health infrastructure.

In order to achieve these set goals collaboration between health care providers and other significant stake holders must be put in place.

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