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close this bookStandard Treatment Guidelines (STG) and The National Essential Drug List for Tanzania (NEDLIT) (WHO; 1997; 210 pages)
View the documentFOREWORD
View the documentACKNOWLEDGMENTS
View the documentINTRODUCTION
close this folderStandard Treatment Guidelines (STG)
close this folder1. GASTROINTESTINAL CONDITIONS
Open this folder and view contents1.1 Parasitic Diseases
View the document1.2 Bacillary Dysentery
close this folder1.3 Diarrhoea
View the document1.3.1 Management of diarrhoea in children
View the document1.3.2 Special Notes on Management
Open this folder and view contents1.4 Cholera
Open this folder and view contents1.5 Ulcers and related conditions
Open this folder and view contents1.6 Other gastro-intestinal problems
Open this folder and view contents1.7 Liver Diseases Conditions
Open this folder and view contents2. RESPIRATORY DISEASES
Open this folder and view contents3. OBSTETRIC AND GYNAECOLOGICAL CONDITIONS AND CONTRACEPTION
Open this folder and view contents4. CARDIOVASCULAR DISEASES
Open this folder and view contents5. MALARIA
Open this folder and view contents6. SKIN DISEASES
Open this folder and view contents7. SEXUALLY TRANSMITTED INFECTIONS / DISEASES (STD)
Open this folder and view contents8. DENTAL AND ORAL CONDITIONS
Open this folder and view contents9. GENITO-URINARY DISEASES: KIDNEY CONDITIONS
Open this folder and view contents10. EAR, NOSE AND THROAT CONDITIONS
Open this folder and view contents11. EYE CONDITIONS
Open this folder and view contents12. TUBERCULOSIS AND LEPROSY
Open this folder and view contents13. MUSCULOSKELETAL CONDITIONS AND JOINT DISEASES
Open this folder and view contents14. METABOLIC AND ENDOCRINE SYSTEM CONDITIONS
Open this folder and view contents15. CENTRAL NERVOUS SYSTEM DISEASE CONDITIONS
Open this folder and view contents16. OTHER DISEASE CONDITIONS
Open this folder and view contents17. VIRAL INFECTIONS
Open this folder and view contents18. ALLERGIC REACTIONS
Open this folder and view contents19. NUTRITIONAL AND HAEMATOLOGIC CONDITIONS
Open this folder and view contents20. MALIGNANT DISEASE CONDITIONS
Open this folder and view contents21. INJURIES AND TRAUMA
View the document22. FOREIGN BODIES
View the document23. PAIN
View the document24. POISONING
View the document25. NORMAL LABORATORY VALUES
Open this folder and view contentsNATIONAL ESSENTIAL DRUG LIST
View the documentABBREVIATIONS AND SYMBOLS
 
1.3.2 Special Notes on Management

Plan A: amount of fluid is in addition to normal feed intake. The health worker must estimate the amount to give for the mother in terms of available utensils.

Plan B: the starting amount is fairly low and must be given frequently in small amounts to avoid vomiting, but must be increased as soon as the child is taking fluid well.

Composition of fluids

“Home fluids”

Any fluids including water, tea, thin porridge, maize-based SSS, but avoiding cold drinks with high sugar content.

Salt/Sugar Solution (SSS)

6 level teaspoons of any household sugar (white or brown), 1/2 teaspoon of salt (coarse salt may have to be ground fine) dissolved in 750 ml of clean water measured in any 750 ml bottle (soft drink, cooking oil etc); it is boiled only if from a contaminated scarce and is cooled before adding ingredients.

Assessment of Dehydration/Other Problems

Look

General Condition

Well, alert

Restless, irritable*

Lethargic, flop*

 

Eyes

Normal

Sunken

Very sunken

 

Mouth & Tongue

Moist

Dry

Very dry

 

Thirst

Not Thirsty

Thirsty, drinks eagerly*

Too ill to drink*

Feel

Skin Pinch

Goes back quickly

Goes back slowly*

Goes back very slowly

 

Fontanelle

Normal

Slightly sunken*

Very sunken*

* If two or more observations with asterisk are present treat according to listed Plan


Decide on degree of dehydration

No Signs of Dehydration

Some Dehydration

Severe Dehydration

Treat according to

PLAN A

PLAN B

PLAN C

Other Problems

• If Blood in stool treat for Bacillary Dysentry (Co - trimoxazole).

• If diarrhoea has lasted 14 days, if has severe malnutrition, refer to hospital for investigation.

• If temperature is 39 degrees or higher, look for other causes of fever and treat


Appropriate Use of Drugs for Children with Diarrhoea

Antibiotics only in dysentery and suspected cholera

Never use Antidiarrheal drugs and antiemetics.

Treatment Plans A, B and C

Plan A: No Sign of Dehydration

Can be treated at home

To prevent dehydration: give more fluids than usual, salt/sugar solution(SSS) or other recommended home fluid.

To prevent malnutrition: continue breast-feeding, offer food 5 to 7 times per day.

Care giver should be advised on:

1. Function of ORS - eg. it does not stop diarrhoea.

2. How much SSS to give 100 ml/kg/day (to nearest half bottle). If vomiting, give fluid slowly by spoon, continue giving more fluid until diarrhoea stops.

3. When to come back to clinic-if worried about condition, vomiting continues, child is eating or drinking poorly, child has fever or blood in the stool, fontanelle is depressed, breathing is difficult or too fast.


Plan B: Some Dehydration

Keep at health center or hospital OPD

Aim to rehydrate over the next 4 hours. Give ORS by cup and spoon. Start with 10 ml/kg/hour, increase as soon as possible to as much as child will take. Continue giving food and breast milk. Constant supervision is essential.

Reassess in 4 hours: If no signs of dehydration, refer to Plan A. If still some signs of dehydration, continue with Plan B. If signs of severe dehydration, refer to Plan C.

If the mother must leave before completing treatment Plan B: Show her how to prepare ORS and how to give the child to complete Plan B and then to follow with Plan A.

Ensure that the mother knows how to prepare SSS at home.

Plan C: Severe Dehydration

Give: Dextrose 5% 30 ml/kg/hour IV, except in cases of severe malnutrition, severe ARI, cardiac problems or neonates who should receive half this volume.

Reassess after one hour: If improving, give 10 ml/kg/hour for the next 5 hours. If not improving and still dehydrated, give 20 ml/kg IV for 1 hour more, then give 10 ml/kg/hour for the next 4 hours. Start oral fluids as soon as patient can drink (usually after 3 to 4 hours). Re-evaluate after 5 hours: If some dehydration persists, then follow Plan B.

Indications for Antibiotic Treatment

Co-trimoxazole (O) Acutely ill child with blood in stool or suspected cholera.

Metronidazole (O) Blood diarrhoea persisting after above, presumed or proved amoebiasis. Persistent diarrhoea with Giardia in the stool.


Drug Doses for Antibiotic Treatment of Diarrhoea

Drug

Age

Dose

Frequency/Duration

Co-trimoxazole 60 mg/kg/24 hrs

4 to 6 months

120 mg (1/4 tablet 480 mg)
= 2.5 ml (of 240 mg/5 ml)

Twice daily for 5 days

 

7 months to 3 years

240 mg (1/2 tablet 480 mg)
= 5 ml (of 240 mg/5 ml)

Twice daily for 5 days

 

3 to 5 years

360 mg (3/4 tablet 480 mg)
= 10 ml (of 240 mg/5 ml)

Twice daily for 5 days

Metronidazole 30 mg/kg/24 hrs

1 to 3 years

200-250 mg

Three times a day for 5 days

 

3 to 7 years

200-250 mg

Four times a day for 5 days

 

7 to 12 years

400-500 mg

Three times a day for 5 days

Rice based Oral Rehydration Fluid

Experience with this type of fluid is limited and guidelines may therefore differ. Different methods of measuring may differ depending on the level of management.

Rice meal: About 50 g or 10-12 level desert spoons or hand scoop of rice is put in.

Water: 1000 ml (2 beer bottle), this is boiled for 10 minutes. Then measure 500 ml (one beer bottle);

Table salt: 1/4 - 1/2 level teaspoon is added and the solution used when cool.

It should be discarded after 6 hours if not fully used.

Full Formula ORS Solution

Made in hospital pharmacies as follows:

ingredient

grams/litre

sodium chloride

3.5 g

trisodium citrate dihydrate (see note)

2.9 g

potassium chloride

1.5 g

glucose, anhydrous

20.0 g

Total

27.9 g

NOTE Trisodium citrate dihydrate may be replaced by sodium bicarbonate 2.5 grams/litre.

However, ORS may be available in packets (sachets) in certain situations according to current Ministry policy.

Acute Diarrhoea and Associated conditions in Adults

Stool should be examined microscopically and cultured. See also HIV related diarrhoea and diarrhoea in children as appropriate.

Gastro-enteritis (Food Poisoning, viral)

Rehydrate - oral fluids in mild cases. IV fluid in more severe cases. If antiemetic is necessary give:

Drug of choice

Promethazine (O)

Adult

25-50 mg in single or divided doses max. 75 mg

Children

1 mg/kg/24 hrs. in 2-3 divided doses

 

Or

 

Promethazine (IM) 25-50 mg in single or divided doses.

Second choice

Chlorpromazine (O)

Adult

10-25 mg every 4-6 hours until vomiting controlled

 

Or

 

Chlorpromazine IM 25 mg initially then 25-50 mg every 3-4 hours until vomiting stops.

NOTE

• Use chlorpromazine drug only when others are not available.

• Antibiotics are NOT required except in special circumstances were infection is suspected.

• Antidiarrhoeals should be avoided.

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