Referral to a specialist is recommended.
General measures (above) are important.
Endoscopic biopsy to exclude malignancy in ALL cases whenever possible.
Cimetidine (O) 800 mg at night for 6 weeks.
Follow-up endoscopy with biopsy should be done after completion of treatment. If ulcer persists, give:
Cimetidine (O) 400 mg four times a day for 6 weeks.
If inadequate response or any evidence of malignancy, refer for treatment of Heterobacter Pyloric and surgery.