Thyphus is a ricketisial disease, which causes an acute febrile illness characterized by an abrupt onset of fever, severe headache and prostration. Important differential diagnosis includes relapsing fever, bacterial meningitis, and thyphoid fever. It is a disease commonly seen among destitute individual with poor personal hygiene.

Diagnosis is by Weil Felix serology test.

Treatment

Tetracycline, 250mg, qid p.o. for 7 days
(For S/E, C/I and dosage forms, see page 5)

OR

Chloramphenicol, 500mg p.o. qid, for 7 days: For children: 25mg/kg.
(For S/E, C/I and dosage forms, see page 7)