Treatment for patients who have been previously exposed to antiretroviral therapy should be discussed with an antiretroviral expert before they are enrolled in the CTC and (re)started on treatment. Overall:
• Those patients controlled on their antiretroviral medication at appropriate doses should continue on the same regimen if possible.
• Those who stopped for reasons other than treatment failure and for whom failure is not suspected can restart the original regimen.
• Those known or suspected to have failed a previous regimen should be started on drugs they have not been exposed to before, as appropriate.