Important clinical signs of response to ARV therapy in children include improvement in growth in children who are failing to grow; improvement in neurological symptoms and development in children who are demonstrating delay in developmental milestones or encephalopathy; and/or decreased frequency of infections (bacterial infections, oral thrush, and/or other opportunistic infections).
Laboratory assessments in children on ARV therapy are the same as recommended in adults. In addition to the clinical assessments recommended in adults, clinical monitoring of ARV treatment in children should include:
Nutrition and nutritional status
Weight and height growth, and head circumference for children under 3 years old.