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close this bookNational Guidelines for the Clinical Management of HIV/AIDS - Tanzania (NACP; 2005; 131 pages)
View the documentLIST OF ABBREVIATIONS
View the documentACKNOWLEDGEMENTS
View the documentFOREWORD
Open this folder and view contentsCHAPTER 1: INTRODUCTION
Open this folder and view contentsCHAPTER 2: ORGANIZATION OF HIV/AIDS CARE AND TREATMENT
Open this folder and view contentsCHAPTER 3: HIV/AIDS PREVENTION
Open this folder and view contentsCHAPTER 4: PROTECTIVE MEASURES AGAINST HIV TRANSMISSION
close this folderCHAPTER 5: LABORATORY TESTS IN HIV/AIDS
Open this folder and view contents5.1 Tests for HIV Diagnosis
View the document5.2 Tests for treatment eligibility and efficacy monitoring
Open this folder and view contents5.3 Tests for treatment safety monitoring
View the document5.4 Laboratory Safety Procedures
View the document5.5 Phlebotomy Safety Procedures
View the document5.6 Sample Storage Procedures
View the document5.7 Sample Transportation Procedure
Open this folder and view contentsCHAPTER 6: HIV/AIDS AND PREGNANCY
Open this folder and view contentsCHAPTER 7: PEDIATRIC HIV/AIDS AND RELATED CONDITIONS
Open this folder and view contentsCHAPTER 8: COMMUNITY AND HOME BASED CARE FOR PEOPLE LIVING WITH HIV/AIDS (PLHA)
Open this folder and view contentsCHAPTER 9: COUNSELLING RELATED TO HIV-TESTING AND TREATMENT ADHERENCE
Open this folder and view contentsCHAPTER 10: MANAGEMENT OF COMMON SYMPTOMS AND OPPORTUNISTIC INFECTIONS IN HIV/AIDS
Open this folder and view contentsCHAPTER 11: MANAGEMENT OF MENTAL HEALTH PROBLEMS IN HIV/AIDS
Open this folder and view contentsCHAPTER 12: MANAGEMENT OF HIV INFECTED PATIENTS USING ANTIRETROVIRAL DRUGS
Open this folder and view contentsCHAPTER 13: ARV THERAPY IN INFANTS AND CHILDREN
Open this folder and view contentsCHAPTER 14: USE OF ARVS IN SPECIAL CIRCUMSTANCES
Open this folder and view contentsCHAPTER 15: HIV/AIDS AND NUTRITION
Open this folder and view contentsCHAPTER 16: MANAGEMENT OF ANTIRETROVIRAL MEDICINES
Open this folder and view contentsCHAPTER 17: CERTIFICATION OF HEALTHCARE FACILITIES AS CARE AND TREATMENT SITES
 

5.2 Tests for treatment eligibility and efficacy monitoring

Table 2: Adult ART First Line Regimens Laboratory Monitoring

Regimen

Monitoring Tests

Frequency

d4T/3TC/EFV

• CD4
• ALT

• Staging, 6-monthly
• 3-monthly

d4T/3TC/NVP

• CD4
• ALT

• Staging, 6-monthly
• Baseline, week 2, thereafter 3 monthly

AZT/3TC/NVP

• CD4
• FBC
• ALT

• Staging, 4-monthly
• 3-monthly
• Baseline, week 2, thereafter 3 monthly

Staging = initial testing for all patients as a qualifying criterion for antiretroviral therapy
Baseline = testing for ART eligible patients, at initiation of ART


Table 3: Adult ART Second Line Regimen Laboratory Monitoring

Regimen

Monitoring Tests

Frequency

AZT/ddI/lopinavir/ritonavir

• CD4
• FBC
• Fasting cholesterol and triglyceride
• Fasting glucose

• Staging, 4-monthly
• Baseline, then 4-monthly
• Baseline, 6 months and thereafter every 12 months
• Every 12 months

Staging = initial testing for all patients as a qualifying criterion for antiretroviral therapy
Baseline = testing for ART eligible patients, at initiation of ART


Table 4: Paediatric ART Regimens and routine monitoring

Regimen

Test

Frequency

d4T/3TC/ritonavir

• CD4
• Fasting cholesterol
• Fasting glucose

• Staging, 6-monthly
• Baseline, 6-monthly
• Baseline, 6-monthly

d4T/3TC/nevirapine

• CD4
• ALT

• Staging, 6-monthly
• Baseline, week 2, 4 and 8, thereafter 6 monthly

AZT/3TC/ritonavir

• CD4
• FBC
• Fasting cholesterol
• Fasting glucose

• Staging, 6-monthly
• Baseline, then monthly for 3 months, then 6 monthly (with CD4) thereafter
• Baseline, 6 monthly
• Baseline, 6-monthly

AZT/3TC/nevirapine

• CD4
• FBC
• ALT

• Staging, 6-monthly
• Baseline, then monthly for 3 months, then 6 monthly (with CD4) thereafter
• Baseline, week 2, 4 and 8, thereafter 6 monthly

d4T/3TC/Lopinavir/ritonavir

• CD4
• Fasting cholesterol
• Fasting glucose

• Staging, 6-monthly
• Baseline, 6-monthly
• Baseline, 6-monthly

d4T/3TC/EFV

• CD4

• Staging, 6-monthly

AZT/3TC/Lopinavir/ritonavir

• CD4
• FBC
• Fasting cholesterol
• Fasting glucose

• Staging, 6-monthly
• Baseline, then monthly for 3 months, then 6 monthly (with CD4) thereafter
• Baseline, 6-monthly
• Baseline, 6-monthly

ddI/AZT/nevirapine

• CD4
• FBC
• ALT

• Staging, 6-monthl
• Baseline, then monthly for 3 months, then 6 monthly (with CD4) thereafter
• Baseline, week 2, 4 and 8, thereafter 6 monthly

ddI/ABC/nevirapine

• CD4
• ALT

• Staging, 6-monthly
• Baseline, week 2, 4 and 8, thereafter 6 monthly

ddI/AZT/EFV

• CD4
• FBC

• Staging, 6-monthly
• Baseline, then monthly for 3 months, then 6 monthly (with CD4)

ddI/ABC/EFV

• CD4

• Staging, 6-monthly

Staging = initial testing for all patients when being referred for antiretroviral therapy.
Baseline = testing for ART eligible patients, at initiation of ART.

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